Anti-Bax Polyclonal Antibody

K001593P-50ul	Solarbio	50ul	960.00元
K001593P-100ul	Solarbio	100ul	1600.00元

英文名称	Rabbit Bax Polyclonal Antibody
应用2	WB IHC IF
克隆类型2	Polyclonal Antibody
别名	BCL2L4
应用	WB,IHC,IF
稀释比例	WB1:500-1:2000 IHC1:50-1:100 IF 1:50 - 1:200
交叉反应	Human Mouse
蛋白分子量	21kDa
Gene ID	581
保存	Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment.
储存液	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant Protein of human Bax
性状	Lyophilized or Liquid
Swiss Prot	Q07812
克隆类型	Polyclonal Antibody
来源	Rabbit
背景资料	The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.